https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Opposing associations of stress and resilience with functional outcomes in stroke survivors in the chronic phase of stroke: a cross-sectional study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45158 N = 70) who had experienced a stroke between 5 months and 28 years ago were included in the cross-sectional study, along with age-matched controls (N = 70). We measured stress using both the Perceived Stress Scale and biological markers, and resilience using both the Brief Resilience Scale and the Connor-Davidson Resilience Scale. Stroke outcomes were assessed using the Stroke Impact Scale. We found that, compared with age-matched controls, stroke survivors reported greater levels of perceived stress, and lower levels of resilience. In stroke survivors, both perceived stress and resilience were independently associated with stroke outcomes in linear regression models. In particular, these relationships were observed for cognitive outcomes including mood, memory, and communication. The association between stress and stroke outcome did not differ across time post stroke. Given that resilience is a modifiable psychological construct, future research may consider whether strategies directed at enhancing resilience may improve recovery from stroke. Australia and New Zealand Clinical Trials Registry: ACTRN12617000736347.]]> Wed 26 Oct 2022 19:17:21 AEDT ]]> Exploring the relationship between fatigue and circulating levels of the pro-inflammatory biomarkers interleukin-6 and C-reactive protein in the chronic stage of stroke recovery: a cross-sectional study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46450 Wed 23 Nov 2022 14:17:48 AEDT ]]> Impaired microglia process dynamics post-stroke are specific to sites of secondary neurodegeneration https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33097 Wed 19 Jan 2022 15:17:31 AEDT ]]> Chronic stress induced disruption of the peri-infarct neurovascular unit following experimentally induced photothrombotic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32497 Wed 17 Nov 2021 16:32:12 AEDT ]]> Chronic stress exposure following photothrombotic stroke is associated with increased levels of Amyloid beta accumulation and altered oligomerisation at sites of thalamic secondary neurodegeneration in mice https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33094 Wed 17 Nov 2021 16:30:26 AEDT ]]> Functional programming of the autonomic nervous system by early life immune exposure: implications for anxiety https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15023 Wed 11 Apr 2018 16:31:59 AEST ]]> Neurobiological consequences of stress: tyrosine hydroxylase phosphorylation in response to stress https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11293 Wed 11 Apr 2018 13:29:03 AEST ]]> The sustained phase of Tyrosine hydroxylase activation in vivo https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17101 Wed 11 Apr 2018 09:35:27 AEST ]]> Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53700 Wed 10 Jan 2024 10:48:50 AEDT ]]> Neuroinflammation as a key driver of secondary neurodegeneration following stroke? https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53699 Wed 10 Jan 2024 10:48:23 AEDT ]]> Oral administration of corticosterone at stress-like levels drives microglial but not vascular disturbances post-stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33101 Wed 09 Feb 2022 15:58:21 AEDT ]]> Reconsidering the role of glial cells in chronic stress-induced dopaminergic neurons loss within the substantia nigra? Friend or foe? https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33093 Wed 04 Sep 2019 09:56:33 AEST ]]> Peripheral lipopolysaccharide challenge induces long-term changes in tyrosine hydroxylase regulation in the adrenal medulla https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33092 Wed 04 Sep 2019 09:56:32 AEST ]]> Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52178 Wed 04 Oct 2023 11:05:28 AEDT ]]> The Macrobrachium rosenbergii nodavirus: a detailed review of structure, infectivity, host immunity, diagnosis and prevention https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49075 Wed 03 May 2023 16:15:21 AEST ]]> Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27809 Wed 02 Mar 2022 14:24:39 AEDT ]]> Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54067 Tue 30 Jan 2024 13:56:39 AEDT ]]> Exploring how low oxygen post conditioning improves stroke-induced cognitive impairment: a consideration of amyloid-beta loading and other mechanisms https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38036 Tue 27 Jul 2021 15:08:13 AEST ]]> Low oxygen post conditioning prevents thalamic secondary neuronal loss caused by excitotoxicity after cortical stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38037 Tue 27 Jul 2021 14:35:35 AEST ]]> Can we use 2,3,5-triphenyltetrazolium chloride-atained brain slices for other purposes? The application of western blotting https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38035 Tue 27 Jul 2021 13:32:27 AEST ]]> Growth hormone treatment promotes remote hippocampal plasticity after experimental cortical stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38034 Tue 27 Jul 2021 12:36:14 AEST ]]> Spatiotemporal analysis of impaired microglia process movement at sites of secondary neurodegeneration post-stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48308 2Y₁₂ was present on non-responsive microglia in the first two weeks after stroke but not at later time points. Finally, both classical microglia activation and loss of process extension are highly correlated with neuronal damage. Our findings highlight the importance of microglia, specifically microglia dynamic functions, to the progression of SND post-stroke, and their potential relevance as modulators or therapeutic targets during stroke recovery.]]> Tue 14 Mar 2023 14:41:54 AEDT ]]> More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43876 Tue 04 Oct 2022 12:35:43 AEDT ]]> Diets and Cellular-Derived Microparticles: Weighing a Plausible Link With Cerebral Small Vessel Disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53405 Thu 23 Nov 2023 13:43:18 AEDT ]]> Sustained administration of corticosterone at stress-like levels after stroke suppressed glial reactivity at sites of thalamic secondary neurodegeneration https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33100 Thu 17 Mar 2022 14:39:58 AEDT ]]> Growth hormone improves cognitive function after experimental stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33090 Thu 13 Jan 2022 10:30:28 AEDT ]]> Growth hormone deficiency is frequent after recent stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33725 Thu 13 Jan 2022 10:30:08 AEDT ]]> Visual discrimination impairment after experimental stroke is associated with disturbances in the polarization of the astrocytic aquaporin-4 and increased accumulation of neurotoxic proteins https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38032 Thu 05 Aug 2021 10:35:41 AEST ]]> Signal transduction pathways and tyrosine hydroxylase regulation in the adrenal medulla following glucoprivation: An in vivo analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9423 Sat 24 Mar 2018 08:39:18 AEDT ]]> The effect of social defeat on tyrosine hydroxylase phosphorylation in the rat brain and adrenal gland https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12480 Sat 24 Mar 2018 08:17:19 AEDT ]]> Neurobiological consequences of acute footshock stress: effects on tyrosine hydroxylase phosphorylation and activation in the rat brain and adrenal medulla https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17102 Sat 24 Mar 2018 08:02:32 AEDT ]]> Early life stress and post-weaning high fat diet alter tyrosine hydroxylase regulation and AT1 receptor expression in the adrenal gland in a sex dependent manner https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20066 Sat 24 Mar 2018 08:00:12 AEDT ]]> mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20866 Sat 24 Mar 2018 07:57:51 AEDT ]]> Chronic stress-induced changes in microglia in determining vulnerability to mood disorders https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29939 Sat 24 Mar 2018 07:31:00 AEDT ]]> Meta-Analysis of Studies on Protection Provided by Different Prophylactic Agents, Their Routes of Administration and Incubation Times Against Nodavirus Infection in Macrobrachium Rosenbergii https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50597 Mon 31 Jul 2023 10:30:43 AEST ]]> Is stroke a neurodegenerative condition? a critical review of secondary neurodegeneration and amyloid-beta accumulation after stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:31937 stroke may induce a neurodegenerative condition. Certainly, this is supported to some degree by the relatively high incidence of dementia after stroke. We begin this review by addressing the available research on human and rodent SND pathology after stroke. We next consider amyloid-β in the context of SND. We discuss what amyloid-β is, how is it made, and introduce some caveats on how amyloid-β measurements should be interpreted. In summary, we conclude that there is now robust pre-clinical evidence demonstrating the presence of amyloid disturbances at sites of SND after stroke. We find, however, that the human literature on the topic is more limited and further work is warranted. While the understanding of amyloid disturbances remains inconclusive in human studies, stroke clearly lead to the development of a neurodegenerative-like condition at the sites of SND, with prominent features such as death of neurons and gliosis]]> Mon 23 Sep 2019 13:48:18 AEST ]]> Similar cognitive deficits in mice and humans in the chronic phase post-stroke identified using the touchscreen-based paired-associate learning task https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42362 Mon 22 Aug 2022 14:08:28 AEST ]]> Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30987 Mon 20 Nov 2023 14:18:12 AEDT ]]> Corticosterone administration alters white matter tract structure and reduces gliosis in the sub-acute phase of experimental stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40655 Fri 22 Jul 2022 14:02:02 AEST ]]> Growth hormone promotes motor function after experimental stroke and enhances recovery-promoting mechanisms within the peri-infarct Area https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38033 Fri 15 Jul 2022 10:39:21 AEST ]]> Peripheral inflammation induces long-term changes in tyrosine hydroxylase activation in the substantia nigra https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49358 Fri 12 May 2023 12:35:29 AEST ]]>